2024 Medical Biotechnology

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Academic unit or major
Graduate major in Life Science and Technology
Instructor(s)
Miura Yutaka  Nishiyama Nobuhiro  Yanagida Yasuko  Kadonosono Tetsuya  Orihara Kanami  Masaki Yoshiaki  Igarashi Ryuji 
Class Format
Lecture    (Livestream)
Media-enhanced courses
Day/Period(Room No.)
Mon1-2()  Thr1-2()  
Group
-
Course number
LST.A504
Credits
2
Academic year
2024
Offered quarter
2Q
Syllabus updated
2024/3/14
Lecture notes updated
-
Language used
English
Access Index

Course description and aims

"Medical bioengineering" is an engineering system for developing technologies to be useful for medical use by using biotechnology techniques. Medical fields to be applied are various diseases including lifestyle diseases such as cancer. In the lecture, students learn the basics in developing materials and technologies to be applied to human beings, and also learn about diagnostic technology using imaging and biomarkers, and drug development such as regenerative medicine, biopharmaceuticals, drug delivery system, and anti-cancer drugs.

Student learning outcomes

Students will acquire the following knowledge by taking Medical bioengineering lectures.
1) Fundamentals of biotechnology for medical applications
2) Cancer biology and cancer therapy
3) Fundamentals and applications of biopharmaceuticals
4) Allergy and antibody
5) Fundamentals and applications of drag delivery system
6) Fundamentals and applications of biosensing
7) Fundamentals and applications of quantum sensors

Keywords

Biomaterial, Pharmacokinetics, Imaging probe, Drug delivery system, Biosensing, Quantum sensor, Lifestyle-related diseases, Allergy, Cancer, Biopharmaceuticals

Competencies that will be developed

Specialist skills Intercultural skills Communication skills Critical thinking skills Practical and/or problem-solving skills

Class flow

・The lecture will be by online (ZOOM system).
・The lecture will be carried out using PPT, and the subject quiz test will be carried out at the end of lecture.
・Please read the lecture materials distributed beforehand in T2SCHOLA and prepare.
・This lecture is all done in English, but there are cases where an overview is introduced in Japanese as necessary.

Course schedule/Required learning

  Course schedule Required learning
Class 1 Introduction of medical biotechnology;Cancer Biology & Cancer Therapy Learn cancer biology and therapy
Class 2 Fundamentals of antibodies and their application to disease diagnosis and pharmaceuticals Acquire knowledge of antibody-based disease diagnosis and pharmaceuticals
Class 3 Fundamentals and applications of nucleic acid therapeutics Learn mechanisms of clinically approved nucleic acid therapeutics
Class 4 Design of nucleic acid therapeutics Acquire knowledge of chemical modifications used in nucleic acid therapeutics
Class 5 Pathophysiology of allergic diseases and their treatment The basic mechanism of the pathophysiology of allergic diseases and their conventional treatment options will be explained
Class 6 Applying antibody reactions to treat refractory conditions Antibody drugs that can be used to treat refractory conditions including allergic diseases will be explained
Class 7 Fundamentals and applications of biosensing technologies Acquire knowledge about biosensing technologies
Class 8 Quantum Sensors for Next-Generation Medicine: Applications in Liquid Biopsy Gain an understanding of the next-generation ultra-early diagnosis technologies enabled by nanoscale quantum sensors
Class 9 Quantum Sensors for Understanding Pathophysiology: Applications in Quantitative Microscopy Imaging Learn how nanoscale quantum sensors enable precise measurements within the biological nano-environment
Class 10 Drug delivery system for cardiovascular disease Acquire knowledge of current status and prospect of DDS against cardiovascular diseases
Class 11 Practical DDS in a pharmaceutical company Learn about DDS in a pharmaceutical company
Class 12 Design of drug delivery system (DDS) based on human body structure Learn how to design DDS based on understanding the human body structure Learn cancer biology
Class 13 DDS drug in use and clinical trials Acquire knowledge of DDS on the market and in advanced stage of development.
Class 14 Biomedical engineering in diagnosis and treatments for diseases Understand new medical biotechnology

Out-of-Class Study Time (Preparation and Review)

To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.

Textbook(s)

None

Reference books, course materials, etc.

Distribute the materials at the beginning of the lecture as necessary, and explain using Power point. The power point used for the lecture is uploaded to the T2SCHOLA in advance, so use it for preparation / review.

Assessment criteria and methods

Impose assignment quiz after each lecture. Decide the grade based on the results of the quiz. No report after lectures.
If your quiz reports are found to contain material plagiarized from literature, including the Internet, your grade will be marked zero,

Related courses

  • LST.A342 : Biomedical Materials
  • LST.A352 : Cell Engineering
  • LST.A401 : Molecular and Cellular Biology
  • LST.A412 : Biomaterial Science and Engineering

Prerequisites (i.e., required knowledge, skills, courses, etc.)

Although there are no special requirements, students who take this course are required to have basic knowledge of biology / biochemistry, such as studying related subjects.

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