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2024　Microbiology

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Academic unit or major
Undergraduate major in Life Science and Technology
Instructor(s)
Hirasawa Takashi  Wachi Masaaki  Kajiwara Susumu 
Class Format
Lecture    (Face-to-face)
Media-enhanced courses
Day/Period(Room No.)
Mon1-2(M-B07(H101))  Thr1-2(M-B07(H101))  
Group
-
Course number
LST.A345
Credits
2
Academic year
2024
Offered quarter
2Q
Syllabus updated
2024/3/14
Lecture notes updated
-
Language used
Japanese
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Course description and aims

This course provides a comprehensive view of microbiology, including the history of microbiology, handlings of microorganisms (isolation, culture and observation of microorganisms), taxonomy, cell growth, structures of microbial cells (Bacteria, Archaea, Eukaryotic microbes), energy metabolism, cellular metabolism, pathogenic microbes, and application of microorganisms.

Student learning outcomes

By the end of this course, students will understand;
1) History of microbiology
2) Handlings of microorganisms (Isolation, culture and observation of microorganisms)
3) Taxonomy (Molecular phylogenetics with 16S rRNA)
4) Mathematical expression of growth of microorganisms
5) Structures of microbial cells (Bacteria, Archaea, Eukaryotic microbes)
6) Energy metabolism of microorganisms
7) Cellular metabolism of microorganisms
8) Pathogenic microbes
9) Application of microbes

Keywords

Molecular phylogenetics, Phylogenetic tree, Bacteria, Archaea, Eukaryotic microbes, Metabolism, Respiration, Fermentation, Pathogenic microbes

Competencies that will be developed

✔ Specialist skills ✔ Intercultural skills Communication skills Critical thinking skills Practical and/or problem-solving skills

Class flow

A summary of the previous lecture is given, followed by the main points of the day's lecture. During lecture, questions may be given to find out if students have learned the material given.

Course schedule/Required learning

  Course schedule Required learning
Class 1 History of microbiology Explain about Louis Pasteur, Robert Koch, and Antonie van Leeuwenhoek
Class 2 Taxonomy (Evolution and molecular phylogenetics) Understand molecular phylogenetics
Class 3 Handlings of microorganisms (Isolation, culture and observation of microorganisms) Understand handing of microorganisms
Class 4 Structures of microorganims: Bacteria, archaea, eukaryotic microbes and virus Understand cell structures of bacteria　and eukaryotic microbes
Class 5 Energy metabolism of microorganisms: Glycolysis, fermentation, respiration, amino acid metabolism, and nucleic acid metabolism Understand glycolysis, TCA cycle and electron transport chain
Class 6 History of microbial fermentation: alcoholic brewing, amino acid fermentation, etc. Understand the microorganisms used in traditional fermentation
Class 7 Review of the first half of the course (classes 1–6) and midterm exam. Revise what was taught during classes 1-6 to prepare for the exam.
Class 8 Microbial growth: Mathematical expressin of growth of microorganisms, celldivision, and factors affecting cell growth Understand growth rate constant and continuous culture
Class 9 Microbial genetics: Transformation, trunsduction and recombination Understand DNA and gene
Class 10 Microbial infection and pathogenesis Understand infection of microorganisms as pathogens and pathways of infection in vivo, etc
Class 11 Pathogenic microorganisms: viruses, bacteria, fungi, protozoa Understand the morphology, properties, and growth of typical viruses, bacteria, fungi, and protozoa that are pathogenic
Class 12 Immunity to infection Understand the pathogenesis of infectious diseases based on the basic human defense mechanisms
Class 13 Prevention and treatment of microbial infections Understand the methods and characteristics of prevention and treatment of infectious diseases
Class 14 Review of the second half of the course (classes 8-13) and final exam. Revise what was taught during classes 8-13 to prepare for the exam.

Out-of-Class Study Time (Preparation and Review)

To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.

Textbook(s)

None

Reference books, course materials, etc.

Handouts will be distributed when necessary.
Brock Biology of Microorganisms (14th edition)

Assessment criteria and methods

Midterm exam: 50%, final exam: 50%

Related courses

  • LST.A203 ： Biochemistry I
  • LST.A218 ： Biochemistry II
  • LST.A208 ： Molecular Biology I
  • LST.A213 ： Molecular Biology II
  • LST.A503 ： Environmental Microbiology

Prerequisites (i.e., required knowledge, skills, courses, etc.)

No prerequisites are necessary, but enrollment in the related courses is desirable except Environmental Microbiology (LST.A503).

Contact information (e-mail and phone)    Notice : Please replace from "[at]" to "@"(half-width character).

Masaaki Wachi (mwachi[at]bio.titech.ac.jp, 5770), Takashi Hirasawa (thirasawa[at]bio.titech.ac.jp, 5780), Susumu Kajiwara (kajiwara.s.aa[at]m.titech.ac.jp, 5715)

Office hours

Students may approach the instructors at the end of class or visit their offices upon securing an appointment through e-mail.

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