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2023　Developmental Biology

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Academic unit or major
Undergraduate major in Life Science and Technology
Instructor(s)
Tanaka Mikiko  Kawakami Atsushi  Tachibana Kazunori  Suzuki Takashi  Shiraki Nobuaki 
Class Format
Lecture    (Face-to-face)
Media-enhanced courses
Day/Period(Room No.)
Tue1-2(WL2-201(W621))  Fri1-2(WL2-201(W621))  
Group
-
Course number
LST.A243
Credits
2
Academic year
2023
Offered quarter
3Q
Syllabus updated
2023/10/2
Lecture notes updated
-
Language used
Japanese
Access Index

Course description and aims

The aim of this class is to understand the basic subjects of developmental biology. Students will understand the processes and the mechanisms of animal development, morphogenesis, mitosis, meiosis, neurogenesis, and organ formation.

Student learning outcomes

By the end of this course, students will be able to understand the processes of animal development, and the molecular background of morphogenesis and organogenesis.

Keywords

Body axis formation, Gastrulation, Mitosis, Meiosis, Neurogenesis, Morphogenesis, Organogenesis

Competencies that will be developed

✔ Specialist skills Intercultural skills ✔ Communication skills ✔ Critical thinking skills ✔ Practical and/or problem-solving skills

Class flow

When required, students will be given a small test or report as an index of purpose achievement.

Course schedule/Required learning

  Course schedule Required learning
Class 1 Basics of developmental biology: Relationship between developmental biology and medicine Understand the mechanisms of genetic and non-genetic congenital diseases, and look back the basis of high school level biology.
Class 2 Basics of developmental biology: Basic biology and stem cells Understand how the knowledge of basic biology is applied to therapeutics, and understand the concept of stem cells.
Class 3 Basics of developmental biology: History and important concepts of biology Understand the process through which developmental biology became modern life science.
Class 4 Formation of axis, germ layers and mesoderm Understand the axis, germ layer formation and mesoderm induction.
Class 5 Drosophila embryogenesis 1: Segmentation Explain the mechanisms of segmentation during Drosophila embryogenesis.
Class 6 Drosophila embryogenesis 2: Homeotic genes Explain the roles of Homeotic genes during early Drosophila embryogenesis.
Class 7 Organogenesis 1: Ectoderm derivatives Explain the mechanisms of development of ectoderm-derived organs.
Class 8 Organogenesis 2: Mesoderm derivatives Explain the mechanisms of development of mesoderm-derived organs.
Class 9 Organogenesis 3: Endoderm derivatives Explain the mechanisms of development of endoderm-derived organs.
Class 10 Cell differentiation and stem cells Explain the characteristics of stem cells and the mechanisms of cell differentiation.
Class 11 germ cells and fertilization Explain the features and the mechanisms of germ cells and fertilization.
Class 12 sex determination Explain the mechanisms of neuronal differentiation and fate determination in neuronal development.
Class 13 Neuronal Development (1): Neurogenesis and fate determination Explain the mechanisms of neuronal differentiation and fate determination in neuronal development.
Class 14 Neuronal Development (2): Neuronal circuit formation and its refinement Explain the mechanisms of neuronal circuit formation and its refinement during neuronal development.
Class 15 Examination or spare day

Out-of-Class Study Time (Preparation and Review)

To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.

Textbook(s)

Principles of Development, Fourth Edition, by Lewis Wolpert and Cheryll Tickle, MEDSI

Reference books, course materials, etc.

Reference books:"Campbell Biology, 10th Edition" by Jane B Reece, et al., "Discover Biology, 5th Edition" by Anu Singh-Cundy and Michael L Cain. Course materials will be provided during class.

Assessment criteria and methods

Academic assessment could be done by the performance in the class, if necessary. The term-end examination will be conducted.

Related courses

  • LAS.B101 ： Fundamental Life Science 1-1
  • LAS.B102 ： Fundamental Life Science 1-2
  • LAS.B103 ： Fundamental Life Science 2-1
  • LAS.B104 ： Fundamental Life Science 2-2
  • LST.A347 ： Evolutionary Biology
  • LST.A203 ： Biochemistry I
  • LST.A218 ： Biochemistry II
  • LST.A208 ： Molecular Biology I
  • LST.A213 ： Molecular Biology II
  • LST.A248 ： Molecular Genetics

Prerequisites (i.e., required knowledge, skills, courses, etc.)

Student are recommended to complete classes of Biochemistry 1 and Molecular biology 1.

Contact information (e-mail and phone)    Notice : Please replace from "[at]" to "@"(half-width character).

Atsushi Kawakami　atkawaka[at]bio.titech.ac.jp　
Mikiko Tanaka　mitanaka[at]bio.titech.ac.jp　
Keiko Nonomura　nonomura.kei[at]bio.titech.ac.jp
Nobuaki Shiraki　shiraki[at]bio.titech.ac.jp　
Takashi Suzuki　suzukit[at]bio.titech.ac.jp　

Office hours

Contact each teachers by e-mail in advance to schedule an appointment.

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