2017 Microbiology

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Academic unit or major
Undergraduate major in Life Science and Technology
Wachi Masaaki  Hirasawa Takashi  Nakashima Nobutaka 
Class Format
Media-enhanced courses
Day/Period(Room No.)
Mon1-2(W621)  Thr1-2(W621)  
Course number
Academic year
Offered quarter
Syllabus updated
Lecture notes updated
Language used
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Course description and aims

This course provides a comprehensive view of microbiology, including the history of microbiology, handlings of microorganisms (isolation, culture and observation of microorganisms), taxonomy, cell growth, structures of microbial cells (Bacteria, Archaea, Eukaryotic microbes), energy metabolism, cellular metabolism, cell-cell interaction, symbiosis and parasitism, pathogenic microbes and infectious diseases, and practical application of microorganisms.

Student learning outcomes

By the end of this course, students will understand;
1) History of microbiology
2) Handlings of microorganisms (Isolation, culture and observation of microorganisms)
3) Taxonomy (Molecular phylogenetics with 16S rRNA)
4) Mathematical expression of growth of microorganisms
5) Structures of microbial cells (Bacteria, Archaea, Eukaryotic microbes)
6) Energy metabolism of microorganisms
7) Cellular metabolism of microorganisms
8) Cell-cell interaction of microorganisms
9) Symbiosis and parasitism
10) Pathogenic microbes and infectious diseases
11) Practical application of microorganisms


Molecular phylogenetics, Phylogenetic tree, Bacteria, Archaea, Eukaryotic microbes, Metabolism, Respiration, Fermentation, Symbiosis, Parasitism, Cell-cell interaction, Infectious disease

Competencies that will be developed

Specialist skills Intercultural skills Communication skills Critical thinking skills Practical and/or problem-solving skills

Class flow

In the first half of class, a summary of the previous lecture is given. In the second half, the main points of the day’s lecture are discussed in detail. Students are asked to check the required learning for each class and be sure to read the related section of the text book as part of preparation and review.

Course schedule/Required learning

  Course schedule Required learning
Class 1 History of microbiology Explain about Louis Pasteur, Robert Koch, and Antonie van Leeuwenhoek
Class 2 Handlings of microorganisms (Isolation, culture and obserbation of microorganisms) Understand how to use microscopes
Class 3 Taxosonomy (Evolution and molecular phylogenetics) Undertand how to generate phylogenetic trees
Class 4 Structures of microorganims (1): Bacteria, archaea, and virus Understand cell structures of Gram-positive and Gram-negative bacteria
Class 5 Structures of microorganisms (2): Eukaryotic microbes (Yeast, fungi, and protists) Understand structures of eukaryoteic cells
Class 6 Energy metabolism of microorganisms (1): Glycolysis and fermentation Understand glycolysis
Class 7 Energy metabolism of microorganisms (2): Respiration and photosynthesis Understand TCA cycle, electron transport chain, and photosynthesis
Class 8 Cellular metabolism: Amino acids, nucleic acids, and so on Understand nitrogen metabolism
Class 9 Microbial growth: Mathematical expressin of growth of microorganisms, celldivision, and factors affecting cell growth Understand growth rate constant and continuous culture
Class 10 Microbial genetics: Transformation, trunsduction and recombination Understand DNA and gene
Class 11 Cell-cell interaction: Biofilm and quorum sensing Understand quorum sensing
Class 12 Symbiosis and parasitism Understand rhizobia and enteric bacteria
Class 13 Pathogenic microbes and infectious diseases Understand virulence factors
Class 14 Application of microorganisms (1): Fermentation and metabolic engineering Understand alcohol fermentation
Class 15 Application of microorganisms (2): Bioremediation and production of antibiotics Understand bioremediation and screening


Brock Biology of Microorganisms (14th edition)

Reference books, course materials, etc.

Handouts will be distributed at the beginning of class when necessary and elaborated on using PowerPoint slides.

Assessment criteria and methods

Final examination

Related courses

  • LST.A203 : Biochemistry I
  • LST.A218 : Biochemistry II
  • LST.A208 : Molecular Biology I
  • LST.A213 : Molecular Biology II
  • LST.A503 : Environmental Microbiology

Prerequisites (i.e., required knowledge, skills, courses, etc.)

No prerequisites are necessary, but enrollment in the related courses is desirable except Environmental Microbiology (LST.A503).

Contact information (e-mail and phone)    Notice : Please replace from "[at]" to "@"(half-width character).

Masaaki Wachi (mwachi[at]bio.titech.ac.jp, 5770), Takashi Hirasawa (thirasawa[at]bio.titech.ac.jp, 5780), Nobutaka Nakashima (nnakashima[at]bio.titech.ac.jp, 3626)

Office hours

Students may approach the instructors at the end of class or visit their offices upon securing an appointment through e-mail.

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