The attitude that materials and biological sciences have supported medical treatments is of great importance. In order to achieve innovations useful to medicine, students must succeed in grasping these very different disciplines through "interfaces," sort out the elements of materials science and engineering, and understand development process of biomedical devices. Students deepen their understanding through group discussions that draw on specific examples such as regenerative medicine, nanomedicine, and diagnostic technology. Lecture topics include surfaces, interfaces, cells, receptors, nanoparticles, collagens, scaffolding, etc.
The goal of this course is to understand the nano-bionics field combined with biological science and materials science, and to think about material factors in biomedical devices and nanomedicine, regenerative medicine and diagnostic technology in the right way. This course aims to impart students with the fundamental knowledge of how to consider the interface of biological tissues and biomaterials, how to apply biomedical devices with different properties, and their basic regulations from an engineering point of view.
This course provides knowledge of the evolution of biomedical devices and builds the foundation of technology related with nanomedicine, regenerative medicine and diagnostics based on a materials science perspective.
Biomaterial, Nanobiotechnology, Medical Device, Nanomedicine, Regenerative Medicine, Diagnostic Technology
|✔ Specialist skills||✔ Intercultural skills||✔ Communication skills||Critical thinking skills||✔ Practical and/or problem-solving skills|
Necessary materials are distributed as the lecture continues. Students should work on necessary exercise problems to gain a deeper understanding of the content from the previous lecture.
|Course schedule||Required learning|
|Class 1||Histroy of Biomedical Devices||Material property in medical use|
|Class 2||Cells||Relationship of biofunction and structure|
|Class 3||Extracellular Matrix and biomimicry||Biomimicry|
|Class 4||Interfacial interaction of materials and cells||Attachement of cells on materials|
|Class 5||Surface Design and nano-bionics||Funcionalization of biomaterials|
|Class 6||Nanomedecine||Medical treatment using nanotechnology|
|Class 7||Preparation and Application of Microparticles||Preparation of Microparticles|
|Class 8||Preparatin and Application of Nanoparticles||Preparation of Nanoparticles|
|Class 9||Detection of Biomolecules based on Materials||Recent biosensing|
|Class 10||Tissue Engineering A||History of Regenerative medicine|
|Class 11||Tissue Engineering B||Regenerative medicine Skin and Cartilage|
|Class 12||Tissue Engineering C||Regenerataive medicine Ligament and Decellularized tissues|
|Class 13||Tissue Engineering D||Bone and cartilage regeneration|
|Class 14||Advanced Medical Devices||Advanced Medical Devices Stent and Bone filling materials|
To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.
Text book specified by the instructor
David Williams "Essential Biomaterials Science" Cambridge University Press, Edited by B.D. Ratner, A.S. Hoffman, F.J. Schoen, J.E. Lemons, "Biomaterials Science An Introduction to Materials in Medicine", Academic Press., Toshiyuki Ikoma, Junzo Tanaka et al. Nanobio and Nanomedicine, Korona-sha
The comprehension about material’s factors in nanomedicine, regenerative medicine and diagnostics, and the attitude about biomedical devices based on material engineering are tested. Learning results are evaluated as the final examination rated at 70% and the group discussion at 30%.