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2024　Organic Chemistry II(C-X) A

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Academic unit or major
Undergraduate major in Chemical Science and Engineering
Instructor(s)
Otsuka Hideyuki 
Class Format
Lecture    (Face-to-face)
Media-enhanced courses
Day/Period(Room No.)
Mon3-4(W3-707(W371))  
Group
A
Course number
CAP.O202
Credits
1
Academic year
2024
Offered quarter
2Q
Syllabus updated
2024/3/14
Lecture notes updated
-
Language used
Japanese
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Course description and aims

[Summary of the course] In this course, synthesis and reactions of organic halides, nucleophilic substitution and elimination reactions of the alkyl halides, and chemistry of conjugated compounds will be explained for the students who study Organic Chemistry.
[Aim of the course] Organohalides are fundamental and essential to understand reactions of various organic compounds. Also, conjugated compounds are useful for synthesis of complex molecules. Students understand chemistry of the organic halide as well as fundamentals of organometallic chemistry. Next, students acquire the ability to discuss the mechanism of the most basic organic reactions, especially nucleophilic substitution reactions, using stereochemical knowledge. Finally, students understand chemistry of conjugated dienes.

Student learning outcomes

By the end of this course, students acquire the following abilities:
(1) Ability to understand basic knowledge about chemistry of organohalides that is the important characteristics of organic
synthesis.
(2) Ability to explain nucleophilic substitution reactions, that is a basic reaction in organic chemistry, using stereochemical knowledge and
way of thinking.
(3) Ability to discuss the reaction mechanism and to draw up a synthetic plan of a target compound, based on (1) and (2) above.
(4) Ability to explain chemistry of conjugated compound.

Keywords

Alkyl halides, organometallic chemistry, nucleophilic substitution reactions, SN2 reactions, SN1 reactions, elimination reactions, electrophilic additions, and conjugated compounds.

Competencies that will be developed

✔ Specialist skills Intercultural skills Communication skills Critical thinking skills ✔ Practical and/or problem-solving skills

Class flow

This course will proceed in the following order: (1) property, synthesis, and reactions of organic halides, (2) reactions of alkyl halides (nucleophilic substitution and elimination reactions), and reactions of conjugated compounds. In the last day, practice problems and interpretation of them will be provided to check the level of understanding.
interpretation of them will be provided to check the level of understanding.

Course schedule/Required learning

  Course schedule Required learning
Class 1 Synthesis of alkyl halides Explain synthesis of alkyl halides.
Class 2 Ractions of alkyl halides, Introduction of organometallic chemistry Explain reactionss of alkyl halides. Explain introduction of organometallic chemistry.
Class 3 SN2 reactions Explain SN2 reactions.
Class 4 SN1 reactions Explain SN1 reactions. chemistry.
Class 5 Comparison between elimination reaction, nucleophilic substitution and elimination Discuss the reaction mechanism and draw up the synthetic plan of the target compound, based on accurate understanding of the mechanism of nucleophilic substitution and elimination reactions.
Class 6 Reactions of conjugated compounds Explain reactions of conjugated compounds.
Class 7 Practice problems and interpretation for confirming the level of understanding Solve practice problems by accurate understanding of the above all lectures.

Out-of-Class Study Time (Preparation and Review)

To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.

Textbook(s)

McMurry Organic Chemistry, international edition of 9th revised edition (Cengage Learning) ISBN: 9784807909124

Reference books, course materials, etc.

Study Guide with Student Solutions Manual for McMurry's Organic Chemistry, 9th edition (Cengage Learning) ISBN: 9784807909155

Assessment criteria and methods

Final examination for confirming the level of understanding (65-85%) and in-class quizzes (15-35%）.

Related courses

  • CAP.O201 ： Organic Chemistry I(Alkanes, Alkenes, Alkynes)
  • CAP.O203 ： Organic Chemistry III(Benzene・C-O)
  • CAP.O204 ： Organic Chemistry IV（C=O・C≡N)

Prerequisites (i.e., required knowledge, skills, courses, etc.)

The condition of the study will not be made, but it is desirable to study Organic Chemistry I (Alkanes, Alkenes, Alkynes).

Contact information (e-mail and phone)    Notice : Please replace from "[at]" to "@"(half-width character).

ito.s.ao[at]m.titech.ac.jp （Shigekazu Ito)
otsuka[at]mac.titech.ac.jp (Hideyuki Otsuka）

Office hours

Make a reservation by an e-mail in advance.

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