2020 Bioprocess Engineering

Font size  SML

Register update notification mail Add to favorite lecture list
Academic unit or major
Undergraduate major in Chemical Science and Engineering
Okochi Mina 
Course component(s)
Lecture    (ZOOM)
Day/Period(Room No.)
Course number
Academic year
Offered quarter
Syllabus updated
Lecture notes updated
Language used
Access Index

Course description and aims

This Bioprocess Engineering course is intended for 3rd year students and focuses on the use of biocatalysts in production and material transformation. The aims of this course are for students to gain fundamental knowledge of enzymes and microorganisms used as biocatalysts, and reaction kinetics and fermentation balance from an engineering perspective. Also, process operation of bioreactor using microorganisms and sterilization process are explained.

Student learning outcomes

By the end of this course, students will be able to:
1) give an overview of microbial characteristics and its utilization in industrial process
2) explain characteristics of enzyme and its reaction kinetics
3) explain characteristics of microbial fermentation and its general kinetics
4) understand bioreactor design and its operation
5) explain sterilization methods and set treatment conditions


Microorganism, Enzyme, Metabolism, Reaction kinetics, Fermentation balance, Bioreactor, Bioseparation

Competencies that will be developed

Specialist skills Intercultural skills Communication skills Critical thinking skills Practical and/or problem-solving skills

Class flow

Toward the end of class, students are given exercise problems related to what is taught in the class.

Course schedule/Required learning

  Course schedule Required learning
Class 1 Bioprocess - Introduction and overall picture Overview biocatalysts utilization in industrial process
Class 2 Microbial metabolism Explain carbon metabolism and energy metabolism
Class 3 Enzyme characteristics and processes Explain characteristics of enzyme and its reaction kinetics
Class 4 Microbial fermentation Explain characteristics of microorganisms and its growth kinetics
Class 5 Fermentation balance, reaction kinetics Explain fermentation balance and growth kinetics
Class 6 Bioreactor, continuous culture Explain characteristics of microbial fermentation using bioreactor and its operating condition
Class 7 Sterilization Explain sterilization methods and set treatment conditions

Out-of-Class Study Time (Preparation and Review)

To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.


Kenji Hashimoto. Hannou Kougaku. Tokyo: Baifukan. ISBN-10: 4563045187.

Reference books, course materials, etc.

Hajime Unno, Kazuhiro Nakanishi eds. Yasunori Tanji, Masanao Imai, Masafumi Yohda, Hiroyasu Ogino. "Biological Chemical Engineering" 3rd edition, Tokyo:Kodansha, ISBN 978-4-06-139831-3.
Takeshi Kobayashi, Hiroyuki Honda. "Biological Chemical Engineering" Tokyo:Tokyo Kagaku Dojin. ISBN 4-8079-1427-8.

Assessment criteria and methods

Exercise problems (60%), report (40%)

Related courses

  • CAP.C207 : Introduction to Biotechnology
  • CAP.C206 : Chemical Reaction Engineering I (Homogeneous System)
  • ZUJ.C301 : Introduction to Biochemical Process
  • CAP.C306 : Chemical Reaction Engineering II (Heterogeneous System)

Prerequisites (i.e., required knowledge, skills, courses, etc.)


Page Top