This Bioprocess Engineering course is intended for 3rd year students and focuses on the use of biocatalysts in production and material transformation. The aims of this course are for students to gain fundamental knowledge of enzymes and microorganisms used as biocatalysts, and reaction kinetics and fermentation balance from an engineering perspective. Also, process operation of bioreactor using microorganisms and sterilization process are explained.
By the end of this course, students will be able to:
1) give an overview of microbial characteristics and its utilization in industrial process
2) explain characteristics of enzyme and its reaction kinetics
3) explain characteristics of microbial fermentation and its general kinetics
4) understand bioreactor design and its operation
5) explain sterilization methods and set treatment conditions
Microorganism, Enzyme, Metabolism, Reaction kinetics, Fermentation balance, Bioreactor, Bioseparation
|✔ Specialist skills||✔ Intercultural skills||Communication skills||Critical thinking skills||Practical and/or problem-solving skills|
Toward the end of class, students are given exercise problems related to what is taught in the class.
|Course schedule||Required learning|
|Class 1||Bioprocess - Introduction and overall picture||Overview biocatalysts utilization in industrial process|
|Class 2||Microbial metabolism||Explain carbon metabolism and energy metabolism|
|Class 3||Enzyme characteristics and processes||Explain characteristics of enzyme and its reaction kinetics|
|Class 4||Microbial fermentation||Explain characteristics of microorganisms and its growth kinetics|
|Class 5||Fermentation balance, reaction kinetics||Explain fermentation balance and growth kinetics|
|Class 6||Bioreactor, continuous culture||Explain characteristics of microbial fermentation using bioreactor and its operating condition|
|Class 7||Sterilization||Explain sterilization methods and set treatment conditions|
To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.
Kenji Hashimoto. Hannou Kougaku. Tokyo: Baifukan. ISBN-10: 4563045187.
Hajime Unno, Kazuhiro Nakanishi eds. Yasunori Tanji, Masanao Imai, Masafumi Yohda, Hiroyasu Ogino. "Biological Chemical Engineering" 3rd edition, Tokyo:Kodansha, ISBN 978-4-06-139831-3.
Takeshi Kobayashi, Hiroyuki Honda. "Biological Chemical Engineering" Tokyo:Tokyo Kagaku Dojin. ISBN 4-8079-1427-8.
Exercise problems (60%), report (40%)