[Summary of the course] In this course, an overview of organic reactions, structure/reactivity/synthesis of alkenes, structure/reactivity/synthesis of alkynes, and retrosynthetic analysis will be explained for the students who studied Organic Chemistry I (Alkanes) (Chemical Science and Engineering).
[The aim of the course] As unsaturated hydrocarbons are the important organic compounds which are used as starting materials for various functional materials and biologically active substances, it is extremely important to understand the chemistry of these classes of compounds. In this course, at first, students understand classification of organic reactions based on the reaction mechanism. Next, students understand structures, reactions, and synthesis of the alkenes and alkynes. Finally, students understand the basis for the planning method of the synthesis of organic compounds by the retrosynthetic analysis.
By the end of this course, students will acquire the following abilities to:
(1) Understand the classification of the reactions based on the reaction mechanism.
(2) Understand structure/reactivity/synthesis of alkenes.
(3) Understand structure/reactivity/synthesis of alkyne.
(4) Understand nature and reactivity of conjugated compounds.
(5) Make a plan for the synthesis of organic compounds.
radical reactions, polar reactions, addition reactions, transition state, activation energy, cis-trans isomerism, nucleophilic addition reactions, Markovnikov rule, carbcation, elimication reactions, retrosynthetic analysis
|✔ Specialist skills||Intercultural skills||Communication skills||Critical thinking skills||✔ Practical and/or problem-solving skills|
This course will proceed in the following order: (1) overview of organic reactions, (2) alkenes, (3) alkynes, (4) conjugated compounds and retrosynthetic analysis. In the last day, practice problems and interpretation of them will be carried out to confirm the level of understanding.
|Course schedule||Required learning|
|Class 1||Overview of organic reactions||Classification of organic reactions based on reaction mechanism.|
|Class 2||Energy Diagrams of reactions||Explain energy diagrams.|
|Class 3||Structure and reactivity of alkenes||Explain nomenclature and reactivity of alkenes.|
|Class 4||Synthesis and reactions of alkenes (halogenation, hydration, hydologenation)||Explain the synthesis and reactions of alkenes (halogenation, hydration, hydologenation) based on the reaction mechanism)|
|Class 5||Reaction of alkene (oxidation, addition of carbenes, hydologenation)||Explain the reactions of alkenes (oxidation, addition of carbenes, hydologenation) hydologenation) based on the reaction. mechanism)|
|Class 6||Synthesis and reactions of alkynes||Explain the synthesis and reactions of alkynes.|
|Class 7||Explain the conjugated compounds and retorsynthetic analysis||Explain the conjugated compounds and retorsynthetic analysis.|
|Class 8||Practice problems and interpretation for confirming the level of understanding||Solve practice problems by accurate understanding of the above all lectures.|
McMurry Organic Chemistry, international edition of 9th edition (Cengage Learning) ISBN-13: 978-0840054531
Study Guide with Student Solutions Manual for McMurry's Organic Chemistry, 9th Edition (Cengage Learning) ISBN-13: 978-1305080485
Practice problems and interpretation for confirming the level of understanding (85%), level of class participation (15%) (The level of class
participation will be calculated by discussion, small examination and so on in the lecture.)
The condition of the study will not be made, but it is desirable to study Organic Chemistry I (Alkanes) (Chemical Science and Engineering).
thiroshi[at]apc.titech.ac.jp (Hiroshi Tanaka)
konishi.g.aa[at]m.titech.ac.jp (Gen-ichi Konishi)
Classes A and B are for the students with an odd and even student ID numbers, respectively.