Interdisciplinary research fields are rapidly expanding in modern society. Therefore, it is important for future researchers to capture challenges based on multidisciplinary insights. This course will provide professional knowledges of interdisciplinary research fields which is important for front-line life engineers in life engineering course. In particular, "Advanced Human Centered Science and Biomedical Engineering II" will focus on advanced interdisciplinary researches between chemistry and life science fields. In this interdisciplinary research field, fusion of knowledges and technologies in each field will lead to development of novel technologies and creation of new interdisciplinary research fields. In this course, students can learn professional knowledges and understand how chemistry and life science fields have merged to have technological innovations through learning particular cases.
By the end of this course, students will be able to :
1) Understand the properties of cancers at the cellular and organ levels and design the future strategies for anti-cancer drug development
2) Explain the principle and the application of super-resolution microscopy and atomic force microscopy
3) Design cell surface by the evaluation of physical property using atomic force microscopy
4) Explain stress responses in photosynthetic organisms and biosensers made of proteins
5) Understand catalytic chemistry related to environmental and energrtic issues
Advanced Human Centered Science and Biomedical Engineering, Tumor microenvironment, Cancer chemotherapy, Super-resolution microscopy, Atomic force microscopy, Protein sensors, Photosynthetic organisms, Catalytic chemistry
|✔ Specialist skills||Intercultural skills||Communication skills||✔ Critical thinking skills||✔ Practical and/or problem-solving skills|
In the first half of the class, the main points of the day's lecture are explained. In the latter half, these main points are discussed in details. Students are asked to provide solutions to some of the questions as necessary. Always check the required learning for each class and be sure to complete it as a part of peparation and review.
|Course schedule||Required learning|
|Class 1||Guidance||Students must be able to understand the course description and amins and the class flow in each class.|
|Class 2||Cancer biology and treatment strategies （Kondoh）||Learn the properties of cancers at the cellular and organ levels and the leading edge of cancer treatments, and understand the difficulties of cancer research for developing new anti-cancer strategies.|
|Class 3||Cancer chemotherapy (Nakamura)||Learn the recent development of cancer chemotherapy and understand the future strategies for anti-cancer drug development.|
|Class 4||Introduction to super-resolution microscopy using 2-color laser spectroscopy and its application to biological samples (Sakai)||Explain the princple and the application of super-resolution microscopy.|
|Class 5||Creation of sensors made of proteins (Ueda)||Students must be able to explain biosensors made of proteins such as antibody and enzyme.|
|Class 6||Stress responses in photosynthetic organisms (Imamura)||Understand molecular mechanism of various stress responses in photosynthetic organisms.|
|Class 7||Catalysts for environment and enregy (Baba)||Understand catalytic chemistry related to environmental and energrtic issues.|
|Class 8||Observation of cell surface by the evaluation of physical property using atomic force microscopy (Mori)||Understand characteristics of cell surface which included physical properties such as strength and modulus as well as height image by using atomic force microscopy.|
Handouts will be distributed at the beginning of class if necessary.
Assessment is based on the quality of the written reports and on the status of submission thereof in each class.
Students are encouraged to complete the related courses.