2017 Biomaterial Science and Engineering

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Academic unit or major
Graduate major in Life Science and Technology
Maruyama Atsushi  Tagawa Yoh-Ichi  Mori Toshiaki  Matsuda Tomoko 
Course component(s)
Day/Period(Room No.)
Mon3-4(J221,W631)  Thr3-4(J221,W631)  
Course number
Academic year
Offered quarter
Syllabus updated
Lecture notes updated
Language used
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Course description and aims

Advanced Biomaterials Engineering involves introduction to anatomy of human tissues and organs, biomaterials science, artificial organs, prosthetic devices, and in vitro living models using microfluidic devices. Biomaterials include polymeric, ceramic, metallic, and other biomimetic materials. At the end of this course, students will be able to: 1) Explain biomaterials. 2) Have an understanding of living body and its reactions, design biomaterials for research and medicine. 3) Design and experiment or draw up research plans, collect and analyze the data obtained , and produce reports based on the findings. 4) Prepare overviews of previously conducted researches, identifiy issues, and propose solutions.

Student learning outcomes

By the end of this course, students will be able to:
1) Use the techniques and modern engineering tools for basic and clinical biomedical study.
2) Understand the properites and applications of biomaterials, both natural and synthetic.
3) Understand the interactions between biomaterials and the human body.Understand how to use biomaterial engineering.


Biomaterial, Matrix, Organ, Tissue, Tissue Engineering, Cell, Regenerative Medicine, Drug Delivery

Competencies that will be developed

Specialist skills Intercultural skills Communication skills Critical thinking skills Practical and/or problem-solving skills

Class flow

In the first quarter of a class, a summary of the previous lecture followed by the main points of the day’s lecture posed as questions are given. Then, these main points are discussed in detail. Always check the required learning for each class and be sure to complete them as a part of preparation and review.

Course schedule/Required learning

  Course schedule Required learning
Class 1 Tissues and Organs Understand aims of this course. Student will be introduced to structures of tissues and organs as outline of human anatomy.
Class 2 Cell Adherent Molecules Students will be provided with cell biology in tissues and organs.
Class 3 Biocompatibility, Sterallization, Safety Students will be introduced how to apply biomaterials for clinic and research.
Class 4 Natural Polymer Biomaterials and Biodegradable Materials Students will be introduced to natural and biodegradable materials for clinical application.
Class 5 Synthetic Polymer Biomaterials Students will be introduced to Synthetic materials for clinical application.
Class 6 Metal biomaterials Students will be provided with an overview of metal biomaterials for clinical application.
Class 7 Ceramics Biomaterials Students will be provided with an overview of ceramics biomaterials for clinical application.
Class 8 Drug Delivery System Understand applications of biomaterials for drug delivery systems.
Class 9 High Performance and Functional Biomaterials Students will be introduced high performance and functional biomaterials.
Class 10 Cell Culture Substrates Understand principles and applicatinos of cell cultures.
Class 11 Biomaterials based on Proteins Students will be provided with recent examples of biomaterials including proteins as functional components are overviewed.
Class 12 Biomaterials based on Nucleic Acids Students will be provided with recent examples of biomaterials including nucleic acids as functional components are overviewed.
Class 13 Biomimetic Materials Students will be provided with history and typical examples of biomimetic materials are overviewed.
Class 14 Regenerative Medicine Students will be provided with an overview of current regenerative medicine using biomaterial technology
Class 15 Microfluidic Devices Students will be provided with microfulidic device technology such as body on a chip.


Essential Biomaterials Science, David Williams, Cambridge University Press

Reference books, course materials, etc.

Molecular Biology of the Cell, 6th Edition (Bruce Alberts et al., Garland Science)
Biochemistry, 4th Edition (Donald Voet, Judith G. Voet, Wiley)

Assessment criteria and methods

1) Students will be assessed on their understanding of each tiopic
2) Students' course scores are based on final exam.
3) Full attendance are compulsory.

Related courses

  • LST.A203 : Biochemistry I
  • LST.A218 : Biochemistry II
  • LST.A208 : Molecular Biology I
  • LST.A213 : Molecular Biology II
  • LST.A336 : Genetic Engineering
  • LST.A342 : Biomedical Materials

Prerequisites (i.e., required knowledge, skills, courses, etc.)

Biochemistry, Molecular Biology, Cell Biology, General Chemistry

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