The attitude that materials and biological sciences have supported medical treatments is of great importance. In order to achieve innovations useful to medicine, students must succeed in grasping these very different disciplines through "interfaces," sort out the elements of materials science and engineering, and understand development process of biomedical devices. Students deepen their understanding through group discussions that draw on specific examples such as regenerative medicine, nanomedicine, and diagnostic technology. Lecture topics include surfaces, interfaces, cells, receptors, nanoparticles, collagens, scaffolding, etc.
The goal of this course is to understand the nano-bionics field combined with biological science and materials science, and to think about material factors in biomedical devices and nanomedicine, regenerative medicine and diagnostic technology in the right way. This course aims to impart students with the fundamental knowledge of how to consider the interface of biological tissues and biomaterials, how to apply biomedical devices with different properties, and their basic regulations from an engineering point of view.
This course provides knowledge of the evolution of biomedical devices and builds the foundation of technology related with nanomedicine, regenerative medicine and diagnostics based on a materials science perspective.
Biomaterial, Nanobiotechnology, Medical Device, Nanomedicine, Regenerative Medicine, Diagnostic Technology
|Intercultural skills||Communication skills||Specialist skills||Critical thinking skills||Practical and/or problem-solving skills|
Necessary materials are distributed as the lecture continues. Students should work on necessary exercise problems to gain a deeper understanding of the content from the previous lecture.
|Course schedule||Required learning|
|Class 1||Histroy of Biomedical Devices||Material property in medical use|
|Class 2||Biomimetic Materials||Relationship of biofunction and structure|
|Class 3||Structure of Biominerals||Mineralization|
|Class 4||Interfacial Interaction of Materials and Cells||Biocompatibility|
|Class 5||Surface Design of Biomaterials||Funcionalization of biomaterials|
|Class 6||Nanomedecine||Medical treatment using nanotechnology|
|Class 7||Preparation and Application of Nanoparticles||Preparation of nanoparticles|
|Class 8||Biological Reaction of Nanoparticles and Cancer Therapy||Cutng edge of cancer therapy|
|Class 9||Detection of Biomolecules based on Materials||Recent biosensing|
|Class 10||Microfludics for Diagnostics||Microanalysis method|
|Class 11||Scaffolds for Regenerative Medicine||Present status and future of regenerative medicine|
|Class 12||Collagen Techonology||Usefullness of collagen in medical treatment|
|Class 13||Application I: Bone and Cartilage||Bone and cartilage regeneration|
|Class 14||Application II: Nerve and Cornea||Nerve and cornea tissue regeneration|
|Class 15||Toward to Application of Bomedical Devices||Regulation and safety|
Text book specified by the instructor
David Williams "Essential Biomaterials Science" Cambridge University Press, Edited by B.D. Ratner, A.S. Hoffman, F.J. Schoen, J.E. Lemons, "Biomaterials Science An Introduction to Materials in Medicine", Academic Press., Toshiyuki Ikoma, Junzo Tanaka et al. Nanobio and Nanomedicine, Korona-sha
The comprehension about material’s factors in nanomedicine, regenerative medicine and diagnostics, and the attitude about biomedical devices based on material engineering are tested. Learning results are evaluated as the final examination rated at 70% and the group discussion at 30%.