2022 Microbiology

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Academic unit or major
Undergraduate major in Life Science and Technology
Wachi Masaaki  Hirasawa Takashi  Yamamoto Naoyuki 
Class Format
Lecture    (Livestream)
Media-enhanced courses
Day/Period(Room No.)
Mon1-2(H106)  Thr1-2(H106)  
Course number
Academic year
Offered quarter
Syllabus updated
Lecture notes updated
Language used
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Course description and aims

This course provides a comprehensive view of microbiology, including the history of microbiology, handlings of microorganisms (isolation, culture and observation of microorganisms), taxonomy, cell growth, structures of microbial cells (Bacteria, Archaea, Eukaryotic microbes), energy metabolism, cellular metabolism, pathogenic microbes, metagenome analaysis, symbiosis, and application of microorganisms.

Student learning outcomes

By the end of this course, students will understand;
1) History of microbiology
2) Handlings of microorganisms (Isolation, culture and observation of microorganisms)
3) Taxonomy (Molecular phylogenetics with 16S rRNA)
4) Mathematical expression of growth of microorganisms
5) Structures of microbial cells (Bacteria, Archaea, Eukaryotic microbes)
6) Energy metabolism of microorganisms
7) Cellular metabolism of microorganisms
8) Pathogenic microbes
9) Metagenome analysis
10) Symbiosis
11) Application of microbes


Molecular phylogenetics, Phylogenetic tree, Bacteria, Archaea, Eukaryotic microbes, Metabolism, Respiration, Fermentation, Pathogenic microbes, Metagenome, Symbiosis

Competencies that will be developed

Specialist skills Intercultural skills Communication skills Critical thinking skills Practical and/or problem-solving skills

Class flow

Lectures are given by the Zoom broadcasting. When necessary, a summary of the previous lecture is given, followed by the main points of the day's lecture. During each lecture, questions may be given to find out if students have learned the material given.

Course schedule/Required learning

  Course schedule Required learning
Class 1 History of microbiology Explain about Louis Pasteur, Robert Koch, and Antonie van Leeuwenhoek
Class 2 Taxonomy (Evolution and molecular phylogenetics) Understand molecular phylogenetics
Class 3 Handlings of microorganisms (Isolation, culture and observation of microorganisms) Understand handing of microorganisms
Class 4 Structures of microorganims (1): Bacteria, archaea, and virus Understand cell structures of Gram-positive and Gram-negative bacteria
Class 5 Structures of microorganisms (2): Eukaryotic microbes (Yeast, fungi, and protists) Understand structures of eukaryoteic cells
Class 6 Energy metabolism of microorganisms (1): Glycolysis and fermentation Understand glycolysis
Class 7 Energy metabolism of microorganisms (2): Respiration and photosynthesis Understand TCA cycle, electron transport chain, and photosynthesis
Class 8 Cellular metabolism: Amino acids, nucleic acids, and so on Understand nitrogen metabolism
Class 9 Microbial growth: Mathematical expressin of growth of microorganisms, celldivision, and factors affecting cell growth Understand growth rate constant and continuous culture
Class 10 Microbial genetics: Transformation, trunsduction and recombination Understand DNA and gene
Class 11 Pathogenic microbes Understand bacterial virulence
Class 12 Metagenome analysis Understand metagenome and its application
Class 13 Symbiosis Understand symbiotic intestinal microflora
Class 14 Application of microbes Understand application of microbes for food industry

Out-of-Class Study Time (Preparation and Review)

To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.



Reference books, course materials, etc.

Handouts will be distributed when necessary.
Brock Biology of Microorganisms (14th edition)

Assessment criteria and methods

Students will be assessed on their ability to describe the basic knowledge on Microbiology given in the course and to utilize the knowledge for problem solving, and students' course scores are based on the reports etc. given in the lectures.

Related courses

  • LST.A203 : Biochemistry I
  • LST.A218 : Biochemistry II
  • LST.A208 : Molecular Biology I
  • LST.A213 : Molecular Biology II
  • LST.A503 : Environmental Microbiology

Prerequisites (i.e., required knowledge, skills, courses, etc.)

No prerequisites are necessary, but enrollment in the related courses is desirable except Environmental Microbiology (LST.A503).

Contact information (e-mail and phone)    Notice : Please replace from "[at]" to "@"(half-width character).

Masaaki Wachi (mwachi[at]bio.titech.ac.jp, 5770), Takashi Hirasawa (thirasawa[at]bio.titech.ac.jp, 5780), Naoyuki Yamamoto(n-yamamoto[at]bio.titech.ac.jp、5105)

Office hours

Students may approach the instructors at the end of class or visit their offices upon securing an appointment through e-mail.

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