2020 Basic Neuroscience

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Academic unit or major
Undergraduate major in Life Science and Technology
Instructor(s)
Ichinose Hiroshi  Suzuki Takashi  Miyashita Eizo  Akama Hiroyuki  Hirota Junji 
Course component(s)
Lecture    (ZOOM)
Day/Period(Room No.)
Tue1-2(W323)  Fri1-2(W323)  
Group
-
Course number
LST.A346
Credits
2
Academic year
2020
Offered quarter
1Q
Syllabus updated
2020/9/18
Lecture notes updated
-
Language used
Japanese
Access Index

Course description and aims

This course will provide a comprehensive review of neural system for "behavior". After an introductory overview of "behavior" from standpoints of the brain, neurons, and genes, cell and molecular biology of neurons, e.g. ion channels, membrane potential, synapses, and neurotransmitter, will be explained. Then, the neural basis of perception (somatic sensation and vision), cognition, and movement will be reviewed.
The aim of the course is to deepen understanding basic neural mechanisms of our perception of external stimuli and reaction to it.

Student learning outcomes

Brain science has been developed based on neuroscience as a multidisciplinary field of computer science, cell and molecular biology, electrophysiology, etc. To pursue a research in brain science, it is necessary to have comprehensive knowledge about neuroscience. Students will have lectures overviewing "Principles of Neural Science", which is a de fact standard textbook. They will be expected to be interested in the brain and to start active learning. By the end of this course, students will be able to acquire basic knowledge about neuroscience for further studies.

Keywords

brain science, neuroscience, behavior, perception, cognition

Competencies that will be developed

Specialist skills Intercultural skills Communication skills Critical thinking skills Practical and/or problem-solving skills

Class flow

Corresponding sections of "Principles of Neural Science" will be overviewed with original data obtained from experiments by each lecturer.

Course schedule/Required learning

  Course schedule Required learning
Class 1 The Brain, Neurons, Circuit, Genes and Behavior Chapters 1 to 4 in "Principles of Neural Science" will be overviewed. (Suzuki) Understand the basic organization of the brain, neurons, circuits, as well as the genes and their roles on behavior.
Class 2 Ion Channels and membrane potential Chapters 5 and 6 in "Principles of Neural Science" will be overviewed. (Suzuki) Understand the structure and function of Ion Channels, as well as the mechanisms of production of resting membrane potential and electrical properties of a nerve cell.
Class 3 Action Potential Chapter 7 in "Principles of Neural Science" will be overviewed. (Suzuki) Understand the mechanisms of production of action potential and electrical properties of a nerve cell.
Class 4 Synaptic transmission, synaptic Integration in the Central Nervous SystemChapter 9 and 10 in "Principles of Neural Science" will be overviewed. (Ichinose) Understand the mechanisms of synaptic transmission and integration of inputs in the central nervous system.
Class 5 Modulation of the synaptic transmission, transmitter release, and neurotransmitters, Chapter 11, 12 and 13 in "Principles of Neural Science" will be overviewed. (Ichinose) Understand the modulation mechanisms of synaptic transmission, synaptic release by second messengers, and the metabolism of neurotransmitters.
Class 6 Neurotransmitters and diseases of the nerve and motor unit Chapters 14, 62, and 63 in "Principles of Neural Science" will be overviewed. (Ichinose) Understand the concepts of neurotransmitters and the molecular mechanisms of disorders caused by impairment of synaptic transmission
Class 7 Sensory Coding and The Somatosensory System, Chapters 22 and 22 in "Principles of Neural Science" will be overviewed. (Hirota) Understand the organizational features common to all sensory systems, and coding and processing in the somatosensory system.
Class 8 The Constructive Nature of Visual Processing, Chapter 25 in "Principles of Neural Science" will be overviewed. (Hirota) Understand the organization and the flow of visual information in the visual system.
Class 9 The Auditory Central Nervous System, Smell and Taste (Chemical Senses), Chapters 31 and 32 in "Principles of Neural Science" will be overviewed. (Hirota) Understand the organization and the information processing in the auditory, olfactory and gustatory systems.
Class 10 The organization and planning of movement Chapter 33 in "Principles of Neural Science" will be overviewed. (Miyashita) Understand what kind of computation has to be done in the brain to execute a movement.
Class 11 The motor unit and spinal reflexes Chapters 34 and 35 in "Principles of Neural Science" will be overviewed. (Miyashita) Understand the characteristics of the muscle as an actuator and spinal reflexes as a feedback control mechanisms.
Class 12 The primary motor cortex in voluntary movement Chapters 37 in "Principles of Neural Science" will be overviewed. (Miyashita) Understand the role of the primary motor cortex in voluntary movement.
Class 13 Neural basis of cognition Chapters 18 and 20 in "Principles of Neural Science" will be overviewed. (Akama) Understand the organization of cognition and functional imaging of cognition.
Class 14 Neural basis of high-order cognition Chapters 60 and 65 in "Principles of Neural Science" will be overviewed. (Akama) Understand the neural mechanisms of language, learning and memory.

Out-of-Class Study Time (Preparation and Review)

To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.

Textbook(s)

None.

Reference books, course materials, etc.

"Principles of Neural Sciences, Fifth edition", edited by Erick R. Kandel et al. McGraw Hill, 2013.
"Neuroscience –Exploring the brain– Fourth edition", edited by Bear MF, Connors BW, and Paradiso MA, 2016
Students should download lecture notes from OCW.

Assessment criteria and methods

Degree of understanding basic knowledge of neuroscience will be evaluated by short tests or assignments at each class, and written examinations at the end of each lecturer.

Related courses

  • LST.A410 : Advanced Neuroscience
  • LAT.A405 : Cognitive Psychology
  • HCB.M461 : Laboratory Training on Human Brain Functions and Their Measurements
  • MEC.L431 : Human Brain Functions and Their Measurements
  • ICT.H509 : Mesurement of Brain Function
  • LAH.T309 : Linguistics C
  • LST.A362 : Evolution and Developmental Biology

Prerequisites (i.e., required knowledge, skills, courses, etc.)

Nothing in particular.

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