This course provides a comprehensive view of microbiology, including the history of microbiology, handlings of microorganisms (isolation, culture and observation of microorganisms), taxonomy, cell growth, structures of microbial cells (Bacteria, Archaea, Eukaryotic microbes), energy metabolism, cellular metabolism, pathogenic microbes, metagenome analaysis, symbiosis, and application of microorganisms.
By the end of this course, students will understand;
1) History of microbiology
2) Handlings of microorganisms (Isolation, culture and observation of microorganisms)
3) Taxonomy (Molecular phylogenetics with 16S rRNA)
4) Mathematical expression of growth of microorganisms
5) Structures of microbial cells (Bacteria, Archaea, Eukaryotic microbes)
6) Energy metabolism of microorganisms
7) Cellular metabolism of microorganisms
8) Pathogenic microbes
9) Metagenome analysis
11) Application of microbes
Molecular phylogenetics, Phylogenetic tree, Bacteria, Archaea, Eukaryotic microbes, Metabolism, Respiration, Fermentation, Pathogenic microbes, Metagenome, Symbiosis
|✔ Specialist skills||✔ Intercultural skills||Communication skills||Critical thinking skills||Practical and/or problem-solving skills|
Lectures are given by the Zoom broadcasting. When necessary, a summary of the previous lecture is given, followed by the main points of the day's lecture. During each lecture, questions may be given to find out if students have learned the material given.
|Course schedule||Required learning|
|Class 1||History of microbiology||Explain about Louis Pasteur, Robert Koch, and Antonie van Leeuwenhoek|
|Class 2||Handlings of microorganisms (Isolation, culture and obserbation of microorganisms)||Understand handing of microorganisms|
|Class 3||Taxosonomy (Evolution and molecular phylogenetics)||Understand molecular phylogenetics|
|Class 4||Structures of microorganims (1): Bacteria, archaea, and virus||Understand cell structures of Gram-positive and Gram-negative bacteria|
|Class 5||Structures of microorganisms (2): Eukaryotic microbes (Yeast, fungi, and protists)||Understand structures of eukaryoteic cells|
|Class 6||Energy metabolism of microorganisms (1): Glycolysis and fermentation||Understand glycolysis|
|Class 7||Energy metabolism of microorganisms (2): Respiration and photosynthesis||Understand TCA cycle, electron transport chain, and photosynthesis|
|Class 8||Cellular metabolism: Amino acids, nucleic acids, and so on||Understand nitrogen metabolism|
|Class 9||Microbial growth: Mathematical expressin of growth of microorganisms, celldivision, and factors affecting cell growth||Understand growth rate constant and continuous culture|
|Class 10||Microbial genetics: Transformation, trunsduction and recombination||Understand DNA and gene|
|Class 11||Pathogenic microbes||Understand bacterial virulence|
|Class 12||Metagenome analysis||Understand metagenome and its application|
|Class 13||Symbiosis||Understand symbiotic intestinal microflora|
|Class 14||Application of microbes||Understand application of microbes for food industry|
To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.
Handouts will be distributed when necessary.
Brock Biology of Microorganisms (14th edition)
Students will be assessed on their ability to describe the basic knowledge on Microbiology given in the course and to utilize the knowledge for problem solving, and students' course scores are based on the reports etc. given in the lectures.
No prerequisites are necessary, but enrollment in the related courses is desirable except Environmental Microbiology (LST.A503).
Masaaki Wachi (mwachi[at]bio.titech.ac.jp, 5770), Takashi Hirasawa (thirasawa[at]bio.titech.ac.jp, 5780), Naoyuki Yamamoto（n-yamamoto[at]bio.titech.ac.jp、5105）
Students may approach the instructors at the end of class or visit their offices upon securing an appointment through e-mail.