2019 Basic Neuroscience

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Academic unit or major
Undergraduate major in Life Science and Technology
Instructor(s)
Ichinose Hiroshi  Suzuki Takashi  Miyashita Eizo  Akama Hiroyuki 
Course component(s)
Lecture
Day/Period(Room No.)
Tue1-2(W323)  Fri1-2(W323)  
Group
-
Course number
LST.A346
Credits
2
Academic year
2019
Offered quarter
1Q
Syllabus updated
2019/4/5
Lecture notes updated
-
Language used
Japanese
Access Index

Course description and aims

This course will provide a comprehensive review of neural system for "behavior". After an introductory overview of "behavior" from standpoints of the brain, neurons, and genes, cell and molecular biology of neurons, e.g. ion channels, membrane potential, synapses, and neurotransmitter, will be explained. Then, the neural basis of perception (somatic sensation and vision), cognition, and movement will be reviewed.
The aim of the course is to deepen understanding basic neural mechanisms of our perception of external stimuli and reaction to it.

Student learning outcomes

Brain science has been developed based on neuroscience as a multidisciplinary field of computer science, cell and molecular biology, electrophysiology, etc. To pursue a research in brain science, it is necessary to have comprehensive knowledge about neuroscience. Students will have lectures overviewing "Principles of Neural Science", which is a de fact standard textbook. They will be expected to be interested in the brain and to start active learning. By the end of this course, students will be able to acquire basic knowledge about neuroscience for further studies.

Keywords

brain science, neuroscience, behavior, perception, cognition

Competencies that will be developed

Intercultural skills Communication skills Specialist skills Critical thinking skills Practical and/or problem-solving skills
- - - -

Class flow

Corresponding sections of "Principles of Neural Science" will be overviewed with original data obtained from experiments by each lecturer.

Course schedule/Required learning

  Course schedule Required learning
Class 1 The Brain, Neurons, Circuit, Genes and Behavior Chapters 1 to 3 in "Principles of Neural Science" will be overviewed. Understand the basic organization of the brain, neurons, circuits, as well as the genes and their roles on behavior.
Class 2 The Cells of the Nervous Sytem and Ion Channels Chapters 4 and 5 in "Principles of Neural Science" will be overviewed. Understand the basic structure and function of nerve cells, as well as the structure and function of Ion Channels.
Class 3 Membrane Potential Chapter 6 in "Principles of Neural Science" will be overviewed. Understand the mechanisms of production of resting membrane potential and electrical properties of a nerve cell.
Class 4 Action Potential Chapter 7 in "Principles of Neural Science" will be overviewed. Understand the mechanisms of production and propagation of electrical signals in a nerve cell.
Class 5 Synaptic transmission, synaptic Integration in the Central Nervous SystemChapter 9 and 10 in "Principles of Neural Science" will be overviewed. Understand the mechanisms of synaptic transmission and integration of inputs in the central nervous system.
Class 6 Modulation of the synaptic transmission, transmitter release Chapter 11 and 12 in "Principles of Neural Science" will be overviewed. Understand the modulation mechanisms of synaptic transmission and synaptic release by second messengers.
Class 7 Neurotransmitters and diseases of the nerve and motor unit Chapters 13 and 14 in "Principles of Neural Science" will be overviewed. Understand the concepts of neurotransmitters and the molecular mechanisms of disorders caused by impairment of synaptic transmission
Class 8 The role of the basal ganglia for integration on sensory inputs and the mechanisms of neurodegenerative disorders. Chapter 43 and 44 in "Principles of Neural Science" will be overviewed. Understanding the role of the basal ganglia and the etiology of neurodegenerative disorders.
Class 9 The Central Nervous System: The Functional Organization of Perception and Movement Chapter 15 and 16 in "Principles of Neural Science" will be overviewed. Understand the functional organization of the central nervous system for perception and movement.
Class 10 Neural Basis of Perception: Somatosensory system and vision Chapters 22 and 25 in "Principles of Neural Science" will be overviewed. Understand the neural mechanisms of perception of somatic sensation and vision.
Class 11 The organization and planning of movement and spinal reflexes Chapters 33 and 35 in "Principles of Neural Science" will be overviewed. Understanding the organization and planning of movement and spinal reflexes.
Class 12 The primary motor cortex and the parietal and premotor cortex in voluntary movement. Chapters 37 and 38 in "Principles of Neural Science" will be overviewed. Understanding the role of the primary motor cortex and the parietal and premotor cortex in voluntary movement.
Class 13 Neural basis of cognition Chapters 18 and 20 in "Principles of Neural Science" will be overviewed. Understand the organization of cognition and functional imaging of cognition.
Class 14 The unconscious and conscious processing of neural information Chapters 48 and 51 in "Principles of Neural Science" will be overviewed. Understand the neural mechanism of emotions, feelings, sleep and dreamings.
Class 15 Neural basis of high-order cognition Chapters 60 and 65 in "Principles of Neural Science" will be overviewed. Understand the neural mechanisms of language, learning and memory.

Textbook(s)

None.

Reference books, course materials, etc.

Principles of Neural Sciences, Fifth edition, edited by Erick R. Kandel et al. McGraw Hill, 2013.
Students should download lecture notes from OCW.

Assessment criteria and methods

Degree of understanding basic knowledge of neuroscience will be evaluated by short tests or assignments at each class, and written examinations at the end of the quarter.

Related courses

  • LST.A410 : Advanced Neuroscience
  • LAT.A405 : Cognitive Psychology
  • HCB.M461 : Laboratory Training on Human Brain Functions and Their Measurements
  • MEC.L431 : Human Brain Functions and Their Measurements
  • ICT.H509 : Mesurement of Brain Function
  • LAH.T309 : Linguistics C
  • LST.A362 : Evolution and Developmental Biology

Prerequisites (i.e., required knowledge, skills, courses, etc.)

Nothing in particular.

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