2021 Advanced Organic Chemistry II (Structure and Function)

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Academic unit or major
Undergraduate major in Chemical Science and Engineering
Ito Shigekazu 
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Course description and aims

[Summary of the course] In this course, first of all, chemical bonds will be reviewed, and π-conjugation including aromaticity will be explained. In addition, chemistry of reaction intermediates will be discussed.
[Aim of the course] Many functional organic compounds such as medicines, biologically active compounds, and electronic materials have been developed based on the structures and physical properties. In this course, students review organic chemistry and acquire the ability to design functional organic compounds.

Student learning outcomes

By the end of this course, students acquire the following abilities to:
(1) Explain characters of chemical bonds.
(2) Explain importance of pai-electron delocalization and aromaticity.
(3) Explain fundamentals of cations, anions, radicals, and carbenes.


chemical bonds, stereochemistry, π-conjugation, aromaticity, reactive intermediates

Competencies that will be developed

Specialist skills Intercultural skills Communication skills Critical thinking skills Practical and/or problem-solving skills

Class flow

This course will proceed in the following order: (1) chemical bonds, (2) π-conjugation, (3) aromaticity, (4) reactive intermediates. In the last day, practice problems and interpretation of them will be carried out to confirm the level of understanding.

Course schedule/Required learning

  Course schedule Required learning
Class 1 Chemical bonds Understand fundamentals of chemical bonds.
Class 2 Chemistry of dienes 1 Explain structure and addition reaction of dienes.
Class 3 Chemistry of dienes 2 Explain cycladdition reaction of dienes.
Class 4 Chemistry of dienes 3 Explain spectroscopic properties of dienes.
Class 5 Aromatic compounds Explain various aromatic compounds including annulenes.
Class 6 Reactive intermediates Explain importance of reactive intermediates for organic synthesis and materials.
Class 7 Practice problems and interpretation for confirming the level of understanding Solve practice problems by accurate understanding of the above all lectures.

Out-of-Class Study Time (Preparation and Review)

To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.


McMurry Organic Chemistry, international edition of 9th revised edition (Cengage Learning) ISBN-13: 978-4-8079-09148

Reference books, course materials, etc.

Kozo Yuki Kagaku (Asakura Kagaku Taikei 4, Asakura Shoten) ISBN 978-4-254-14634-9

Assessment criteria and methods

Practice problems and interpretation for confirming the level of understanding (50%), level of class participation (50%) (The level of class
participation will be calculated by discussion, small examination and so on in the lecture.)

Related courses

  • CAP.B212 : Organic Chemistry II (Alkenes)
  • CAP.B213 : Organic Chemistry III (Aromatic Compounds)
  • CAP.B214 : Organic Chemistry IV (Nucleophilic Substitution)
  • CAP.B315 : Organic Chemistry V (Carbonyl Compounds)
  • CAP.B316 : Organic Chemistry VI (Amines)
  • CAP.B211 : Organic Chemistry I (Alkanes) (Chemical Science and Engineering)

Prerequisites (i.e., required knowledge, skills, courses, etc.)

The condition of the study will not be made, but it is desirable to study Organic Chemistry I (Alkanes) (Chemical Science and Engineering),
Organic Chemistry II (Alkenes), Organic Chemistry III (Aromatic Compounds), Organic Chemistry IV (Nucleophilic Substitution), and Organic Chemistry VI (Amines).

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