2019 Advanced Course of Nano-Bionics

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Academic unit or major
Graduate major in Materials Science and Engineering
Ikoma Toshiyuki 
Course component(s)
Day/Period(Room No.)
Tue3-4(S7-201)  Fri3-4(S7-201)  
Course number
Academic year
Offered quarter
Syllabus updated
Lecture notes updated
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Course description and aims

The attitude that materials and biological sciences have supported medical treatments is of great importance. In order to achieve innovations useful to medicine, students must succeed in grasping these very different disciplines through "interfaces," sort out the elements of materials science and engineering, and understand development process of biomedical devices. Students deepen their understanding through group discussions that draw on specific examples such as regenerative medicine, nanomedicine, and diagnostic technology. Lecture topics include surfaces, interfaces, cells, receptors, nanoparticles, collagens, scaffolding, etc.

Student learning outcomes

The goal of this course is to understand the nano-bionics field combined with biological science and materials science, and to think about material factors in biomedical devices and nanomedicine, regenerative medicine and diagnostic technology in the right way. This course aims to impart students with the fundamental knowledge of how to consider the interface of biological tissues and biomaterials, how to apply biomedical devices with different properties, and their basic regulations from an engineering point of view.
This course provides knowledge of the evolution of biomedical devices and builds the foundation of technology related with nanomedicine, regenerative medicine and diagnostics based on a materials science perspective.


Biomaterial, Nanobiotechnology, Medical Device, Nanomedicine, Regenerative Medicine, Diagnostic Technology

Competencies that will be developed

Specialist skills Intercultural skills Communication skills Critical thinking skills Practical and/or problem-solving skills

Class flow

Necessary materials are distributed as the lecture continues. Students should work on necessary exercise problems to gain a deeper understanding of the content from the previous lecture.

Course schedule/Required learning

  Course schedule Required learning
Class 1 Histroy of Biomedical Devices Material property in medical use
Class 2 Biomimetic Materials Relationship of biofunction and structure
Class 3 Structure of Biominerals Mineralization
Class 4 Interfacial Interaction of Materials and Cells Biocompatibility
Class 5 Surface Design of Biomaterials Funcionalization of biomaterials
Class 6 Nanomedecine Medical treatment using nanotechnology
Class 7 Preparation and Application of Nanoparticles Preparation of nanoparticles
Class 8 Biological Reaction of Nanoparticles and Cancer Therapy Cutng edge of cancer therapy
Class 9 Detection of Biomolecules based on Materials Recent biosensing
Class 10 Microfludics for Diagnostics Microanalysis method
Class 11 Scaffolds for Regenerative Medicine Present status and future of regenerative medicine
Class 12 Collagen Techonology Usefullness of collagen in medical treatment
Class 13 Application I: Bone and Cartilage Bone and cartilage regeneration
Class 14 Application II: Nerve and Cornea Nerve and cornea tissue regeneration
Class 15 Toward to Application of Bomedical Devices Regulation and safety


Text book specified by the instructor

Reference books, course materials, etc.

David Williams "Essential Biomaterials Science" Cambridge University Press, Edited by B.D. Ratner, A.S. Hoffman, F.J. Schoen, J.E. Lemons, "Biomaterials Science An Introduction to Materials in Medicine", Academic Press., Toshiyuki Ikoma, Junzo Tanaka et al. Nanobio and Nanomedicine, Korona-sha

Assessment criteria and methods

The comprehension about material’s factors in nanomedicine, regenerative medicine and diagnostics, and the attitude about biomedical devices based on material engineering are tested. Learning results are evaluated as the final examination rated at 70% and the group discussion at 30%.

Related courses

  • MAT.C316 : Biomaterials Science
  • MAT.C204 : Kinetics of Chemical Reaction (Ceramics course)
  • MAT.C202 : Crystal and Phonon

Prerequisites (i.e., required knowledge, skills, courses, etc.)

No prerequisites

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