The goal is for students to learn basic knowledge of approaches to synthetic chemistry and synthesis methods for organic and polymeric materials.
Molecular structure design based on fundamental concepts of organic synthetic chemistry is important for the development of organic and polymeric materials. The most suitable raw materials and reactive agents, and precise exploration of reaction pathways are necessary for creating high-performance, high-function materials from low-cost starting materials. The instructor in this course will introduce basic concepts of retrosynthesis chemistry as an approach to synthetic organic methods, with the goal of students learning diverse functional group transformation reactions and bond-forming methods.
retrosynthesis, organic and polymeric material, functional group transformation, molecular design
✔ Specialist skills | Intercultural skills | Communication skills | ✔ Critical thinking skills | ✔ Practical and/or problem-solving skills |
The class will move forward in line with handout contents. Handouts are distributed as necessary at the beginning of class. The instructor will go over and review the content of the previous class at the start of class. The instructor will solve practice problems during class, supplementing careful explanations. It is recommended that students prepare and review before and after class based on handout materials.
Course schedule | Required learning | |
---|---|---|
Class 1 | An overview of organic synthesis | Explain the purpose of the lecture and how to proceed. |
Class 2 | Basic concepts of the retrosynthesis for organic chemistry | Understanding the concept of retrosynthesis in organic chemistry must be required. |
Class 3 | Retrosynthesis: alkyl halide | Understanding the synthesis of alkyl halide based on the concept of retrosynthesis must be required. Students must be able to explain the importance of the points. |
Class 4 | Retrosynthesis: alcohol, ether, amine (1) | Understanding the synthesis of alcohols based on the concept of retrosynthesis must be required. Students must be able to explain the importance of the points. |
Class 5 | Retrosynthesis: alcohol, ether, amine (2) | Understanding the synthesis of amines based on the concept of retrosynthesis must be required. Students must be able to explain the importance of the points. |
Class 6 | Retrosynthesis: 1- and 2-substituted alcohols, amines | Understand and explain the synthesis of 1- and 2-substituted alcohols and amines from the concept of retrosynthesis. |
Class 7 | Retrosynthesis: carboxylic acid and its derivatives | Understanding the synthesis of carboxylic acid and its derivatives based on the concept of retrosynthesis must be required. Students must be able to explain the importance of the points. |
Class 8 | Summary: Exam | Understand the structure and stability of Understand and explain the concept of retrosynthetic analysis and each reaction in a comprehensive manner. |
To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterward (including assignments) for each class.
They should do so by referring to textbooks and other course material.
nothing special
Hiroshi Takahashi, The concept of organic synthesis method, Sankyo Publishing, ISBN4-7827-0195-0
Organic Synthesis, Christine L. Willis, Martin Wills, Tokyo Kagaku Dojin, ISBN978-4-7598-0816-2
The grade is mainly evaluated based on the results of the term-end examination.
It is desired that students have taken Organic Synthetic Chemistry A, Organic Synthetic Chemistry B, Organic Chemistry (Reaction-A), and Organic Chemistry (Reaction-B).
hayakawa.t.ac[at]m.titech.ac.jp
Instructor's office: South Bldg. 8, Rm 813, 8th Fl. Contact by e-mail in advance to schedule an appointment.