This course focuses on an important matter about biomaterials and basic knowledge of bioceramics, biopolymers and cells used in medical devices, regenerative medicine and drug delivery system. Biomaterial is an interdisciplinary field, and students need to understand each subject based on a common platform. The selection of materials starts development of medical devices, regenerative medicine and drug delivery systems, and thus students require to understand the properties of materials and cells composed of our tissues and organs.
The goal of this course is to understand fundamental concepts of medical devices, regenerative medicine and drug delivery systems, through the position of material engineering, based on reactivity and safety of biomaterials used in our body, and to explain interfacial interaction between biomaterials and cells.
Biomaterial, Regenerataive Medicine, Drug Delivery System, Bioceramcs, Biopolymers
|✔ Specialist skills||Intercultural skills||Communication skills||Critical thinking skills||Practical and/or problem-solving skills|
This lecture is given by distribution of necessary handout and blackboard demonstration.. Students are given exercise problems related to the lecture given that day to solve. Required learning should be completed outside of the classroom for preparation and review purposes.
|Course schedule||Required learning|
|Class 1||Important matters of biomaterials and medical devices||To understand matters of biomaterials|
|Class 2||Reaction of materials in our body and safety exam||Biocompatibility|
|Class 3||Introduction of bioceramics||Properties of bioceramics|
|Class 4||Biomineralization and hierarchical structure||Structure and function|
|Class 5||Elements of experimental technique (1): Characterization method||Characterization of biomaterials|
|Class 6||Elements of experimental technique (2): Surface and interface analysis||Analytical method of surface and interface|
|Class 7||Introduction of biopolymers||Properties of biopolymers|
|Class 8||Polymer scaffolds and its fabrication method||Application of biopolymers|
|Class 9||Cell and materials (1): Stem cell, structure and function, cell membrane||Stem cell function|
|Class 10||Cell and materials (2): Development, cell genealogy, controlling factors||To understand cells|
|Class 11||Cell and materials (3): Cell engineering, regenerative medicine||Specialized study of regenerative medicine|
|Class 12||Medical technology (1): Bone and cartilage regeneration using regenerative medicine||Specialized study of regenerative medicine|
|Class 13||Medical technology (2): Artificial bone and bone filling materials||Cutting edge of bone treatments|
|Class 14||Medical technology (3): Drug delivery system||Subjects of DDS|
|Class 15||Clinical application of medical devices||Regulation of medical devices|
Junzo Tanaka, Toshiyuki Ikoma, Toshimasa Uemura, Kenichi Ohmori, Bioceramics, Korona-sha
T. Ｉkoma and J. Tanaka et al., Nanobio and Nanomedicine, Korona-sha
Students will be assessed on their understanding of bioceramics, biopolymers, medical devices, regenerative medicines and drug delivery system, and their ability to apply them to solve problems. The student's course scores are based on final exams (80%) and exercises (20%).