2017 Practical Exercises for Advanced Instrumental Measurements III

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Academic unit or major
Chemistry
Instructor(s)
Ohmori Ken  Kudo Fumitaka  Takaya Jun  Ando Yoshio  Takikawa Hiroshi  Sase Shohei  Miyanaga Akimasa 
Course component(s)
Exercise
Day/Period(Room No.)
Intensive ()  
Group
-
Course number
ZSD.A433
Credits
1
Academic year
2017
Offered quarter
1-2Q
Syllabus updated
2017/3/17
Lecture notes updated
-
Language used
Japanese
Access Index

Course description and aims

In this course, students operate instruments for mass spectrometry and NMR to determine the structures of organic molecules. Then, students attempt to solve the structure of the target molecules based on the mass and NMR data. The lecturers teach how to operate these instruments and how to analyze the obtained data. We discuss about the strategy for structural determination of organic molecules.

Nowadays, mass and NMR (including 2D NMR) analysis are widely taken for structural determination of relatively small organic molecules. Students will be able to take such spectra by themself and analyze the data for structural determination.

Student learning outcomes

By the end of this course, students will be able to:
1) Determine the structure of relatively small organic molecules.
2) Operate instruments for mass and NMR by themself
3) Analyze mass spectra and NMR spectra including 2D NMR data for structural determination

Keywords

Structural analysis of organic molecules, structure determination, mass spectral analysis, NMR, 2D-NMR

Competencies that will be developed

Intercultural skills Communication skills Specialist skills Critical thinking skills Practical and/or problem-solving skills
- - -

Class flow

In the first half of the class, we will discuss about previous spectral analysis taken by students. In the latter half, the lecturer teaches a main topic according to the course schedule. Students analyze mass spec and NMRs outside of the classroom.

Course schedule/Required learning

  Course schedule Required learning
Class 1 Introduction to structural analysis of organic compounds Decide a target sample for analysis
Class 2 Mass spectral analysis of organic compounds Mass spectral analysis and make a report
Class 3 1H-NMR 1H-NMR analysis and make a report
Class 4 13C-NMR 13C-NMR analysis and make a report
Class 5 COSY COSY analysis and make a report
Class 6 HMQC, HMBC HMQC, HMBC analysis and make a report
Class 7 NOE NOE analysis and make a report
Class 8 Structural determination of organic compounds Final report

Textbook(s)

Course materials are provided during class.

Reference books, course materials, etc.

Spectrometric Identification of Organic Compounds

Assessment criteria and methods

Exercise problems in each class (60%) and a final report (40%)

Related courses

  • Practical Exercises for Advanced Instrumental Measurements I
  • ZSD.A433 : Practical Exercises for Advanced Instrumental Measurements III
  • Structural Organic Chemistry

Prerequisites (i.e., required knowledge, skills, courses, etc.)

No prerequisites are necessary. But, students who have a credit for Practical Exercises for Advanced Instrumental Measurements I or Practical Exercises for Advanced Instrumental Measurements II, cannot take this class.

Contact information (e-mail and phone)    Notice : Please replace from "[at]" to "@"(half-width character).

Fumitaka Kudo: fkudo[at]chem.titech.ac.jp

Office hours

Students may approach the instructors at the end of class or contact by e-mail in advance to schedule an appointment.

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