The student will learn how they understand and consider the biological events in living cells in terms of organic chemistry. To do so, the student will learn structures and functions of DNA, RNA, proteins, glycans, lipids based on organic chemistry. Particularly, the student will learn how low molecular weight compounds interact with the biomolecules resulting in better understanding of the biological events.
The aim of the course is that the student will understand and consider the structure and function of biomolecules including DNA, RNA, proteins, glycans, polyketides, terpenoids in terms of organic chemistry. The student will understand how low molecular weight compounds interact with the biomolecules resulting in better understanding of the biological events.
chemical biology, mode of action, interaction between biomolecules and small molecules, DNA, RNA, peptides, proteins, glycans, polyketides, terpenoids, signal transduction, receptor proteins
|✔ Specialist skills||Intercultural skills||Communication skills||Critical thinking skills||Practical and/or problem-solving skills|
|Course schedule||Required learning|
|Class 1||Introduction to bioorganic chemistry and chemical biology||Overview of chemical biology|
|Class 2||The chemical origins of biology||Understanding of the chemical origins of biology|
|Class 3||DNA structure and function||Understanding of DNA structure and function|
|Class 4||DNA as a target for drugs||Understanding of DNA as a target for drugs|
|Class 5||RNA structure and function||Understanding of RNA structure and function|
|Class 6||Translational system as a target for drugs||Understanding of translational system as a target for drugs|
|Class 7||Peptide and protein structure||Understanding of peptide and protein structure|
|Class 8||Protein function||Understanding of protein function|
|Class 9||Enzyme reactions and inhibitors||Understanding of enzyme reactions and inhibitors|
|Class 10||Glycobiology||Understanding of glycobiology|
|Class 11||Polyketides chemistry||Understanding of polyketides chemistry|
|Class 12||Terpenoids||Understanding of terpenoids chemistry|
|Class 13||Fundamental of signal transduction||Understanding of fundamental of signal transduction|
|Class 14||Receptor proteins and small molecules in signal transduction||Understanding of receptor proteins and small molecules in signal transduction|
To enhance effective learning, students are encouraged to spend approximately 100 minutes preparing for class and another 100 minutes reviewing class content afterwards (including assignments) for each class.
They should do so by referring to textbooks and other course material.
”Introduction to bioorganic chemistry and chemical biology” CRC Press (Taylor & Francis Group)
Exercise problems including homework in each class (30%) and a final exam (70%)
An understanding of the fundamentals of organic chemistry is required for this course.