2019 Organic Synthesis

Font size  SML

Register update notification mail Add to favorite lecture list
Academic unit or major
Undergraduate major in Chemistry
Instructor(s)
Ohmori Ken  Suzuki Keisuke 
Course component(s)
Lecture
Day/Period(Room No.)
()  
Group
-
Course number
CHM.D331
Credits
2
Academic year
2019
Offered quarter
4Q
Syllabus updated
2019/3/18
Lecture notes updated
-
Language used
Japanese
Access Index

Course description and aims

This is a continuation of Organic Chemistry III. This course focuses on multistep synthesis of organic compounds, particularly introducing synthetic approaches to natural products.

Student learning outcomes

At the end of this course, students will be able to have an understanding of basic concept of retrosynthesis and to learn about various synthetic methodology en route to complex natural products.

Keywords

organic chemistry
synthetic organic chemistry
natural product synthesis

Competencies that will be developed

Intercultural skills Communication skills Specialist skills Critical thinking skills Practical and/or problem-solving skills
- - - -

Class flow

Attendance is taken in every class.

Course schedule/Required learning

  Course schedule Required learning
Class 1 History of organic synthesis and examples for chemical syntheses of complex molecules. Exercise problems might be given in this class.
Class 2 Concept of retro synthetic analysis I: latent polarity Exercise problems might be given in this class.
Class 3 Concept of retro synthetic analysis II: synthons Exercise problems might be given in this class.
Class 4 Formation of multiple C-C bonds, Wittig reaction, elimination Exercise problems might be given in this class.
Class 5 Formation of multiple C-C bonds, other methods Exercise problems might be given in this class.
Class 6 Synthesis of polycyclic compound: cyclization Exercise problems might be given in this class.
Class 7 Synthesis of polycyclic compound: annulation Exercise problems might be given in this class.
Class 8 Exercise I: basic problems Exercise problems might be given in this class.
Class 9 Synthesis of chiral compound I: use of chiral synthons Exercise problems might be given in this class.
Class 10 Synthesis of chiral compound II: asymmetric reaction Exercise problems might be given in this class.
Class 11 Synthesis of alkaloids I: general approach Exercise problems might be given in this class.
Class 12 Synthesis of alkaloids II: construction of polycyclic skeleton Exercise problems might be given in this class.
Class 13 Exercise II: application problems Exercise problems might be given in this class.
Class 14 Synthesis of prostaglandins I: Corey lactone Exercise problems might be given in this class.
Class 15 Synthesis of prostaglandins II: other approaches Exercise problems might be given in this class.

Textbook(s)

None required

Reference books, course materials, etc.

None required

Assessment criteria and methods

Students’ course scores are based on final exams (ca. 70%) and exercise problems (30%) and also attendance.

Related courses

  • CHM.D201 : Organic Chemistry I
  • CHM.D202 : Organic Chemistry II
  • CHM.D301 : Organic Chemistry III

Prerequisites (i.e., required knowledge, skills, courses, etc.)

Students require basic knowledge of organic chemistry.

Page Top