Although the life is so complicated as to seem to be mysterious, the microscopic and molecular elementary processes consist of simple physical events. However, when those simple events run together and fuse into each other, not only the complexity will be raised, but also qualitatively different ‘physical phenomena’ will be generated. That is the essence of the life. Biophysics deals with the ultimate physical phenomena created by the nature in the eternal flow of time. In this course, novel pictures of life drawn by biophysics will be shown, and approaches to reveal the essence of the life by the biophysics will be summarized.
Biophysics is an area of natural science to tackle the eternal problem of life and death by means of physics. In the twentieth century, owing to the rapid advance of modern physics and technology, observation of life activities has become molecular level. As a result the knowledge of life has been expanded the knowledge of life enormously. Will the humankind become able to completely understand life and conquer death? To start with a long journey to answer this question, the very basic knowledge will be provided in this course.
Life Science, Biophysics, Molecular Biology
✔ Specialist skills | Intercultural skills | Communication skills | Critical thinking skills | Practical and/or problem-solving skills |
Lecture
Course schedule | Required learning | |
---|---|---|
Class 1 | Introduction: Summary of biomolecules | Introduction |
Class 2 | Principles of functional architecture of proteins | Functional architecture of proteins |
Class 3 | Principles of functional architecture of nucleic acids | Functional architecture of nucleic acids |
Class 4 | Phasing approaches to observe biomolecules: Circular dichroism (CD), Surface plasmon resonance (SPR), Mass spectrometry, Solution small angel X-ray/neutron scattering, Nuclear magnetic resonance (NMR) | Circular dichroism (CD), Surface plasmon resonance (SPR), Mass spectrometry, Solution small angel X-ray/neutron scattering, Nuclear magnetic resonance (NMR) |
Class 5 | Surface plasmon resonance (SPR), Mass spectrometry, Solution small angel X-ray/neutron scattering, Nuclear magnetic resonance (NMR) | Circular dichroism (CD), Surface plasmon resonance (SPR), Mass spectrometry, Solution small angel X-ray/neutron scattering, Nuclear magnetic resonance (NMR) |
Class 6 | Understanding of the life using biophysics 1(case studies): Molecular mechanism of signaling on bio-membrane micro-domain. | Molecular mechanism of signaling on bio-membrane micro-domain. |
Class 7 | Understanding of the life using biophysics 2(case studies): Molecular mechanism of signaling on bio-membrane micro-domain. | Molecular mechanism of signaling on bio-membrane micro-domain. |
There are no prior conditions for taking the course.
There are no prior conditions for taking the course.
Attendance and Reports
There are no prior conditions for taking the course.