Organic Synthesis

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Lecturer
Atsumi Kunio   
Place
Tue5-6(G113)  
Credits
Lecture2  Exercise0  Experiment0
Code
95047
Syllabus updated
2008/10/1
Lecture notes updated
2008/10/1
Semester
Fall Semester

Outline of lecture

This lecture will be focused on the basic and advanced organic synthesis. The former will mainly cover the design, synthesis and functionalization of supramolecules in terms of the development of optical and electronic materials. The latter will deal with the roles of organic synthesis in research and development of new drugs. Some studies in pharmaceutical companies are explained as examples.

Purpose of lecture

This lecture focuses on the basic and advancedorganic synthesis. The former will mainly cover the carboanionic C-C bond formations. The latter will deal with the roles of organic synthesis in research and development of new drugs. Some studies in pharmaceutical companies are explained as examples.

Plan of lecture

1.Introduction
2.Enolate-1: Acidity-basicity
3.Enolate-2: Reactivity dependent on the functional groups
4.Enolate-3: Selectivity
5.Enolate-4: Aldol reaction
6.Organometallic chemistry
7.Other C-C bond formations
8.Introduction of last half and basics of medicinal chemistry-1
9.Basic of medical chemistry-2
10.Biochemistry and chemistry of b-lactam antibiotics
11.Research and development of b-lactam antibiotics in some pharmaceutical companies.
12.Synthetic studies of b-lactam antibiotics (1)
13.Synthetic studies of b-lactam antibiotics (2)
14.Synthetic studies of b-lactam antibiotics (3)

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