生体分子機能論   Advanced Course of Biological Molecular Function

文字サイズ 

担当教員
相澤 康則 
使用教室
火3-4(B221)  
単位数
講義:2  演習:0  実験:0
講義コード
78001
シラバス更新日
2011年4月6日
講義資料更新日
2011年3月24日
学期
前期

講義概要

The goal of this course is to provide basic knowledge and common sense regarding genomics, one of the fastest growing modern scientific disciplines. Especially, the genome that will be focused on is ours, the human genome. This course covers broad topic areas: genome (gene, retrotransposon), transcriptome (mRNA, noncoding RNA, processed pseudogene, TUF) , epigenome (DNA methylation, histone code, imprinting), comparative genomics (human vs. chimpanzee) and biomedical implications (polymorphism, GWAS). Basic experimental techniques and modern technologies for analyzing genome and gene function will be also emphasized. Each class will be a combination of lecture and class discussions. Reading assigned papers and high quality performance in the class discussion are required from all the students.

講義の目的

The goal of this course is to provide basic knowledge and common sense regarding genomics, one of the fastest growing modern scientific disciplines. Students will also read milestone papers and interpret data on human genomics in the classes to enhance their understanding on genomics.

講義計画

Part I: Brief history and basics of genome mapping and sequencing
Part II: Genomics
Part III: Transcriptome
Part IV: Epigenome (DNA methylation, histone
Part V: Comparative and biomedical genomics (between human and chimpanzee and between us)

教科書・参考書等

References will be announced in the classes.

関連科目・履修の条件等

N/A

成績評価

Attendance, performance in class discussion

担当教員の一言

Students will be required to prepare for class discussion by reading assigned paper(s).

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