- Lecturer
- Aizawa Yasunori
- Place
- Tue3-4(B221)
- Credits
- Lecture2 Exercise0 Experiment0
- Code
- 78001
- Syllabus updated
- 2011/4/6
- Lecture notes updated
- 2011/3/24
- Semester
- Spring Semester
Outline of lecture
The goal of this course is to provide basic knowledge and common sense regarding genomics, one of the fastest growing modern scientific disciplines. Especially, the genome that will be focused on is ours, the human genome. This course covers broad topic areas: genome (gene, retrotransposon), transcriptome (mRNA, noncoding RNA, processed pseudogene, TUF) , epigenome (DNA methylation, histone code, imprinting), comparative genomics (human vs. chimpanzee) and biomedical implications (polymorphism, GWAS). Basic experimental techniques and modern technologies for analyzing genome and gene function will be also emphasized. Each class will be a combination of lecture and class discussions. Reading assigned papers and high quality performance in the class discussion are required from all the students.
Purpose of lecture
The goal of this course is to provide basic knowledge and common sense regarding genomics, one of the fastest growing modern scientific disciplines. Students will also read milestone papers and interpret data on human genomics in the classes to enhance their understanding on genomics.
Plan of lecture
Part I: Brief history and basics of genome mapping and sequencing
Part II: Genomics
Part III: Transcriptome
Part IV: Epigenome (DNA methylation, histone
Part V: Comparative and biomedical genomics (between human and chimpanzee and between us)
Textbook and reference
References will be announced in the classes.
Related and/or prerequisite courses
N/A
Evaluation
Attendance, performance in class discussion
Comments from lecturer
Students will be required to prepare for class discussion by reading assigned paper(s).
