Enhancing seismic performance of urban infrastructures is essential to mitigate loss of function of urban areas during and after a significant earthquake. Seismic design of urban infrastructures is an important part of securing the seismic performance of urban aveas. Emphasis of this lecture will be placed on the seismic design of transportation facilities including bridges and underground structures in soft soil deposits. It has been revealed in the 1994 Northridge, USA earthquake and 1995 Kobe, Japan earthquake that bridges and underground structures are vulnerable to near-field ground motions. The 1999 Bolu, Turkey earthquake and the Chi Chi, Taiwan earthquake resulted in the significant damage of bridges and underground structures by fault-induced displacements. Presented in this lecture are the characterization of ground motions, past damage of transportation facilities, linear and nonlinear dynamic response of bridges and underground structures, effect of poundings, strength and ductility of reinforced concrete piers, columns and walls, performance goals and performance-based seismic design, seismic deformation method, and seismic evaluation and seismic retrofit.