- Lecturer
- Kazarian Sergei
- Place
- Wed5-8(W833,J221)
- Credits
- Lecture1 Exercise0 Experiment0
- Code
- 25049
- Syllabus updated
- 2015/4/6
- Lecture notes updated
- 2015/3/16
- Semester
- Spring Semester
Outline of lecture
Modern process industries are increasingly focussed on advanced product engineering including foods, pharmaceuticals, personal care products, advanced materials, and other formulated products. An integral component of product engineering is the ability to describe the physical chemical attributes of the final product.
This course is designed to provide students with current knowledge and experience in vibrational spectroscopic techniques (Infrared and Raman) for product and process characterization.
Following completion of this course the students will be able to recognise the most relevant spectroscopic technique of choice to analyse a product (including its limitations and benefits). At the end of the course the student should be able to demonstrate knowledge of fundamentals and applications of current spectroscopic methods for materials characterization. Students will also be familiar with the broad areas of applicability of studies spectroscopic methods. The students will also be able to apply the skills learned in the demonstration exercise during the first lecture to the real-world products.
Purpose of lecture
For understanding of vibrational spectroscopy (Infrared and Raman), principles of spectroscopy are introduced first, based on the fundamental concepts of physical chemistry. Then the applications of vibrational spectroscopy to chemical products and processing, such as in the pharmaceutical industry, are discussed. Recent advances in instrumentation and measuring techniques are introduced.
Plan of lecture
1. Fundamentals of vibrational spectroscopy
- What is spectroscopy?
- Interaction of light with matter
- Molecular vibrations and energy levels
- Harmonic oscillator and anharmonicity
- Selection rules
2. Introduction to infrared spectroscopy
- Modes of measurements
- Quantitative law
- Live demonstration of measurements of infrared spectra
- Applications of spectroscopy for product characterisation
- FT-IR spectroscopy, portable spectrometers and accessories
- Attenuated Total Reflection (ATR) and accessories
3. Applications of infrared spectroscopy
- Polymers
- Processing of materials with supercritical fluids.
- Pharmaceuticals
4. FTIR spectroscopic imaging
- Fundamentals and instrumentation
- ATR-FTIR spectroscopic imaging
- Applications in polymer and pharmaceutical industry
- Applications in industry
5. - Applications of spectroscopic imaging
- Imaging in transmission
- Imaging of microfluidic flows
- Biological and forensic applications
6. Introduction to Raman spectroscopy
- Principles, selection rules and instrumentation.
- Applications to polymeric materials
- Applications in industry
- Tip-enhanced Raman spectroscopy for nanotechnology
7. Recent advances in spectroscopic imaging and other modern techniques
Textbook and reference
窶｢ Atkins P. W. 窶廣tkins窶 Physical Chemistry窶 (Oxford University Press, 7th, 8th, 9th,10th Editions).
窶｢ Smith A. L. 窶廣pplied Infrared Spectroscopy窶
窶｢ Hollas J. M. 窶廝asic Atomic and Molecular Spectroscopy窶 (RSC)
窶｢ Ball D. W. 窶弃hysical Chemistry窶 (Thomson Brooks/Cole)
窶｢ Stuart B. 窶廬nfrared Spectroscopy: fundamentals and applications窶
Related and/or prerequisite courses
Physical Chemistry. This course is also relevant to Materials Science and Engineering, Organic and Polymeric Materials, Chemical Engineering, Applied Chemistry, Chemistry and Materials Science
Evaluation
Short written test will include several brief questions on the topics studied in the lectures. Answers will be marked.
Comments from lecturer
First lecture on Wednesday 8/04/2015 will include demonstration of measurements of infrared spectra of selected samples. A small FTIR spectrometer will be available during the lecture to demonstrate that spectra may be measured quickly and their interpretation can be achieve.
Slides of each lecture will be provided on OCW in advance of each lecture as pdf files.
